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chromatography+columns+HyClone+products+(Cytiva)
Catalog Number:
(102979-950)
Supplier:
Adipogen
Description:
PARP-1 (ARTD1) is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. PARP-1 positively regulates the transcription of MTUS1 and negatively regulates the transcription of MTUS2/TIP150. It forms a complex with EEF1A1 and TXK that acts as a T-helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production.
Supplier:
PeproTech, Inc.
Description:
Produced from sera of rabbits immunized with highly pure Recombinant Human G-CSF. AntiHuman G-CSFspecific antibody was purified by affinity chromatography and then biotinylated.
Catalog Number:
(77439-738)
Supplier:
Bioss
Description:
ATP-dependent RNA helicase required during spermatogenesis (PubMed:10920202, PubMed:21034600). Required to repress transposable elements and preventing their mobilization, which is essential for the germline integrity (By similarity). Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons (By similarity). Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycle (By similarity). Required for PIWIL2 slicing-triggered piRNA biogenesis: helicase activity enables utilization of one of the slice cleavage fragments generated by PIWIL2 and processing these pre-piRNAs into piRNAs (By similarity).
Supplier:
Sartorius
Description:
The arium® mini Essential Ultrapure Water benchtop system is designed for direct connection to a pre-treated water supply.
Supplier:
Caron Products
Description:
With full visible and UVA ICH Q1B exposures in as little as 42 hours, the 7450 series provides results fast. Many competing chambers take 2 to 3 times as long. Fast photoexposure allows users to test more samples, reducing drug development time, and saving money.
Catalog Number:
(76120-336)
Supplier:
Bioss
Description:
The smallest of the human chromosomes, 21 makes up about 1.5% of the human genome. Chromosome 21 contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer's disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21. Translocations are found to occur between chromosome 21 and 8, and chromosome 21 and 12, in certain leukemias. The C21orf62 gene product has been provisionally designated C21orf62 pending further characterization.
Catalog Number:
(76120-344)
Supplier:
Bioss
Description:
The smallest of the human chromosomes, 21 makes up about 1.5% of the human genome. Chromosome 21 contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer's disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21. Translocations are found to occur between chromosome 21 and 8, and chromosome 21 and 12, in certain leukemias. The C21orf58 gene product has been provisionally designated C21orf58 pending further characterization.
Supplier:
PeproTech, Inc.
Description:
Produced from sera of rabbits immunized with highly pure Recombinant Human IL-4. AntiHuman IL-4specific antibody was purified by affinity chromatography and then biotinylated.
Supplier:
PeproTech, Inc.
Description:
Produced from sera of rabbits immunized with highly pure Recombinant Human MIA-2. AntiHuman MIA-2specific antibody was purified by affinity chromatography and then biotinylated.
Supplier:
PeproTech, Inc.
Description:
Produced from sera of rabbits immunized with highly pure Recombinant Human BD-4. AntiHuman BD-4specific antibody was purified by affinity chromatography and then biotinylated.
Supplier:
PeproTech, Inc.
Description:
Produced from sera of goats immunized with highly pure Recombinant Human IL-2. AntiHuman IL-2specific antibody was purified by affinity chromatography and then biotinylated.
Catalog Number:
(10366-156)
Supplier:
Bioss
Description:
Nuclear factor kappa B (NFkB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NFkB mediates the expression of a great variety of genes in response to extracellular stimuli including IL1, TNF alpha, and bacterial product LPS. NFkB is associated with IkB proteins in the cell cytoplasm, which inhibit NFkB activity. IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKK alpha and IKK beta). IKK alpha and IKK beta interact with each other and both are essential for NFkB activation. IKK alpha specifically phosphorylates IkBa. IKKa is expressed in variety of human tissues.
Catalog Number:
(76099-084)
Supplier:
Bioss
Description:
Representing approximately 6% of the human genome, chromosome 4 contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. Chromosome 4 reportedly contains the largest gene deserts (regions of the genome with no protein encoding genes) and has one of the two lowest recombination frequencies of the human chromosomes. The C4orf40 gene product has been provisionally designated C4orf40 pending further characterization.
Supplier:
PeproTech, Inc.
Description:
Produced from sera of rabbits immunized with highly pure Recombinant Human VEGF. AntiHuman VEGFspecific antibody was purified by affinity chromatography and then biotinylated.
Catalog Number:
(10096-300)
Supplier:
Proteintech
Description:
TARBP2 is a component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC). Within the complex, TARBP2 and DICER1 are required to process precursor miRNAs (pre-miRNA) to mature miRNA and then load them onto EIF2C2/AGO2. It may has a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1. Otherwise, it binds to the HIV-1 TAR RNA that is located in the long terminal repeat (LTR) of HIV-1, and stimulates translation of TAR-containing RNAs.
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