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electrophoresis+reagents+HyClone+products+(Cytiva)
Catalog Number:
(10490-082)
Supplier:
Bioss
Description:
Acyl-coenzyme A synthetases (ACSs) are a large family of related enzymes known to catalyze the fundamental initial reaction in fatty acid metabolism. The ACS family is roughly characterized based on fatty acid chain length preference amongst different members. The nomenclature in the ACS family reflects this relationship and includes short-chain ACS (ACSS), medium-chain ACS (ACSM), long-chain ACS (ACSL) and very long-chain ACS (ACSVL). ACSVL family members are capable of activating both long (LCFAs) and very long-chain fatty acids (VLCFAs). There are six members of the human ACSVL subfamily, which have been described as solute carrier family 27A (SLC27A) gene products. They represent a group of evolutionarily conserved fatty acid transport proteins (FATPs) recognized for their role in facilitating translocation of long-chain fatty acids across the plasma membrane. The family nomenclature has recently been unified with their respective acyl-CoA synthetase family designations: ACSVL1 (FATP2), ACSVL2 (FATP6), ACSVL3 (FATP3), ACSVL4 (FATP1), ACSVL5 (FATP4) and ACSVL6 (FATP5). ACSVLs have unique expression patterns and are found in major organs of fatty acid metabolism, such as adipose tissue, liver, heart and kidney. ACSVL2 is a 619 amino acid multi-pass membrane protein. Encoded by a gene that maps to human chromosome 5q23.3, ACSVL2 may function as the predominant fatty acid protein transporter in heart.
Supplier:
Biotium
Description:
This antibody recognizes an 85-115 kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1) (Workshop IV). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. W-CAM-1 MAb blocks aggregation of cell lines mediated by the ICAM-1 and blocks homotypic binding of purified populations of activated T- and B-lymphocytes and also aggregation of mixed T- and B-cell blasts. It inhibits T-cell adhesion to normal human endothelial cells. Activation induced by cell-cell contact (mixed lymphocyte reaction, T-cell mediated B-cell activation) is significantly inhibited. This MAb blocks elements of both effector arms of immune system (cytotoxic cell function and Ig production).
CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.
Catalog Number:
(CA1.10013.0001)
Supplier:
MilliporeSigma
Description:
The sulfite test is suitable for food analysis, particularly in the testing of wine and fruit juices, sulfurated foods (e.g
Supplier:
SILICYCLE INC. CA
Description:
With its SiliaSep™ line, SiliCycle offers pre-packed Flash cartridges of superior performance.
Catalog Number:
(10107-182)
Supplier:
Prosci
Description:
MTA2 has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling.This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacteylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis.
Catalog Number:
(CA600-144-200)
Supplier:
Rockland Immunochemical
Description:
Primary Goat Anti-Glutathione-S-Transferase (GST) Reacts with Pan
Catalog Number:
(CA600-145-200)
Supplier:
Rockland Immunochemical
Description:
Primary Goat Anti-Glutathione-S-Transferase (GST) Reacts with Pan
Supplier:
Sartorius
Description:
The arium comfort systems produce ASTM Type 1 ultrapure water and Type 2 pure water.
Catalog Number:
(RC22504)
Supplier:
Ricca Chemical
Description:
0.1% (w/v) Aqueous Solution. Poly bottle. 120mL
Catalog Number:
(CA600-444-378)
Supplier:
Rockland Immunochemical
Description:
Primary Rabbit Anti-V5 TAG Reacts with Pan
Catalog Number:
(CA95036-208)
Supplier:
Spectrum Chemicals
Description:
Tartaric Acid, Granular, NF is used as an antioxidant, acidifier, flavor enhancer, stabilizer and sequestering agent. All Spectrum Chemical NF products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities
Supplier:
Ricca Chemical
Description:
Hematoxylin Stain Solution, Gill 3 Formulation, Triple Strength, for Frozen or Plastic Imbedded Sections, and for More Intense Nuclei in Progressive Histology Staining
Catalog Number:
(470029-780)
Supplier:
EDUCATIONAL & SCIEN. PRODUCT
Description:
Exceptional Model Of A Commonly Studied Organism
Catalog Number:
(470021-706)
Supplier:
Walter Products
Description:
Protect Your Scope During Storage or Transportation
Catalog Number:
(CA600-445-382)
Supplier:
Rockland Immunochemical
Description:
Primary Rabbit Anti-6X HIS EPITOPE TAG Reacts with Pan
Catalog Number:
(CA101641-566)
Supplier:
New England Biolabs (NEB)
Description:
E. coli RecA is necessary for genetic recombination, reactions involving DNA repair and UV-induced mutagenesis. RecA promotes the autodigestion of the lexA repressor, umuD protein and lambda repressor. Cleavage of LexA derepresses more than 20 genes. In vitro studies indicate that in the presence of ATP, RecA promotes the strand exchange of single-strand DNA fragments with homologous duplex DNA. The reaction has three distinct steps: (i) RecA polymerizes on the single-strand DNA, (ii) the nucleoprotein filament binds the duplex DNA and searches for a homologous region, (iii) the strands are exchanged.
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