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electrophoresis+reagents+HyClone+products+(Cytiva)
Catalog Number:
(470150-030)
Supplier:
G-Biosciences
Description:
Hands-on Study of Immunoprecipitation
Supplier:
Biolegend
Description:
PE anti-human CD49d [9F10]; Isotype: Mouse IgG1, κ; Reactivity: Human, African Green, Baboon, Cat (Feline), Cattle (Bovine, Cow), Chimpanzee, Common Marmoset, Cynomolgus, Dog (Canine), Horse (Equine), Rhesus, Sheep (Ovine), Squirrel Monkey; Apps: FC; Size: 100 tests
Supplier:
Biolegend
Description:
APC anti-human CD49d [9F10]; Isotype: Mouse IgG1, κ; Reactivity: Human, African Green, Baboon, Cat (Feline), Cattle (Bovine, Cow), Chimpanzee, Common Marmoset, Cynomolgus, Dog (Canine), Horse (Equine), Rhesus, Sheep (Ovine), Squirrel Monkey; Apps: FC; Size: 100 tests
Supplier:
Stemcell Technologies
Description:
Interleukin 1 alpha (IL-1α) is a member of the IL-1 family and a dual-function cytokine. Both the unprocessed precursor and a processed IL-1α protein signal through IL-1 receptor type 1 (IL-1R1). Various cells, including keratinocytes, thymic epithelium, hepatocytes, endothelial cells, fibroblasts, and the epithelial cells of mucous membranes, have high levels of intracellular IL-1α precursor. The precursor is also expressed on the surface of monocytes and B lymphocytes (Netea <i>et al.</i>). IL-1α recruits infiltrating cells to a site of injury during necrosis and plays an important role during processes of sterile inflammation (Cohen <i>et al.</i>; Rider <i>et al.</i>). During hypoxia, IL-1α contributes to angiogenesis (Carmi <i>et al.</i>). Studies in mice show that IL-1α is produced by microglia-like cells after ischemic brain injury, which contributes to the inflammation (Luheshi <i>et al.</i>).
Supplier:
Stemcell Technologies
Description:
Interleukin 6 (IL-6) is a pleiotropic growth factor with a wide range of biological activities in immune regulation, hematopoiesis, and oncogenesis. IL-6 is produced by a variety of cell types including T cells, B cells, monocytes and macrophages, fibroblasts, hepatocytes, vascular endothelial cells, and various tumor cell lines. On its own or in combination with other factors such as IL-2 and interferon-γ, IL-6 stimulates the proliferation of B cells, T cells, and hybridoma cells (Nordan <i>et al.</i>; Van Snick <i>et al.</i>; Gauldie <i>et al.</i>; Mihara <i>et al.</i>; Tanaka et al). In combination with cytokines such as IL-3, GM-CSF, and SCF, IL-6 has been shown to promote hematopoietic progenitor cell proliferation and differentiation in vitro. IL-6 signals through a cell surface type I cytokine receptor complex consisting of the ligand-binding IL-6α (CD126) and the signal-transducing gp130 subunits. The binding of IL-6 to its receptor system includes activation of the JAK/STAT signaling pathway (Mihara <i>et al.</i>; Peters et al; Tanaka <i>et al.</i>).
Catalog Number:
(MSPP-100-0582)
Supplier:
Stemcell Technologies
Description:
Chimeric mouse (V), human (C) monoclonal IgG antibody against SARS-CoV, SARS-CoV-2 (2019-nCoV) S protein (HEK293-expressed recombinant).
Catalog Number:
(MSPP-100-1320)
Supplier:
Stemcell Technologies
Description:
Use Interleukin 37 (IL-37) to inhibit the expression of inflammatory cytokines, such as IL-6, MIP-1α, MIP-1β, and TNF-α, in a MAPK-dependent manner (Qi <i>et al.</i>). A secreted protein belonging to the interleukin-1 cytokine family, IL-37 acts as an anti-inflammatory alarmin, with predominant expression in monocytes, and constitutive secretion by myeloid dendritic cells (Rudloff <i>et al.</i>). IL-37 has been shown to limit inflammation in human blood M1 macrophages by binding to extracellular surface receptors, requiring IL-1R8 as a coreceptor (Li <i>et al.</i>). It also has protective effects against obesity-induced inflammation and insulin resistance, reducing adipogenesis and activating AMPK signaling both <i>in vitro</i> and <i>in vivo</i> (Ballak <i>et al.</i>). In humans, the IL-37 gene undergoes alternative splicing, resulting in multiple isoforms of the protein (Boraschi <i>et al.</i>). For consistency and reproducibility across your applications, Interleukin 37 from STEMCELL comes lyophilized with ≥ 93% purity.
Catalog Number:
(MSPP-781001006)
Supplier:
Stemcell Technologies
Description:
RANTES (regulated upon activation, normal T cell expressed and secreted), also known as CCL5, is a member of the CC family of chemokines and is able to recruit leukocytes to sites of inflammation (Schall <i>et al.</i>). RANTES is secreted by T lymphocytes, macrophages, platelets, synovial fibroblasts, tubular epithelium, and certain types of tumor cells (Aldinucci and Colombatti; Soria and Ben-Baruch). This chemokine exerts its effect by interacting with the chemokine receptors CCR1, CCR3, CCR4, and CCR5. RANTES plays an active role in recruiting a variety of leukocytes into inflammatory sites, including T cells, macrophages, eosinophils, and basophils. In collaboration with certain cytokines that are released by T cells such as IL-2 and IFN-γ, RANTES also induces the activation and proliferation of NK cells to generate CC chemokine-activated killer cells, which are highly cytolytic (Lv <i>et al.</i>; Maghazachi <i>et al.</i>). It has been shown that RANTES produced by CD8+ T cells inhibits HIV infection of primary human peripheral blood mononuclear cells (Appay and Rowland-Jones; Cocchi <i>et al.</i>).
Supplier:
Biolegend
Description:
Pacific Blue™ anti-human CD86 [IT2.2]; Isotype: Mouse IgG2b, κ; Reactivity: Human, African Green, Baboon, Capuchin Monkey, Common Marmoset, Cotton-topped Tamarin, Chimpanzee, Cynomolgus, Rhesus; Apps: FC; Size: 100 tests
Supplier:
Biolegend
Description:
PE anti-human CD25 [M-A251]; Isotype: Mouse IgG1, κ; Reactivity: Human, Cross-Reactivity: Baboon, Cynomolgus, Rhesus; Apps: FC; Size: 100 μg
Supplier:
Biolegend
Description:
Alexa Fluor® 488 anti-human HLA-DR [L243]; Isotype: Mouse IgG2a, κ; Reactivity: Human, African Green, Baboon, Chimpanzee, Cynomolgus, Dog (Canine), Marmoset, Rhesus, Squirrel Monkey, Tamarin; Apps: FC; Size: 100 μg
Catalog Number:
(CA89007-934)
Supplier:
Brady Worldwide
Description:
Brady has super-tough smear-proof ribbons assure your printed text lasts for years outdoors and in an industrial environment
Catalog Number:
(89285-578)
Supplier:
Genetex
Description:
Monoclonal Antibody to CD48 (Human) Fluorescein (FITC)
Supplier:
Biolegend
Description:
APC anti-mouse CD301 (MGL1/MGL2) [LOM-14]; Isotype: Rat IgG2b, κ; Reactivity: Mouse; Apps: FC; Size: 100 μg
Supplier:
Biolegend
Description:
Brilliant Violet 605™ anti-human CD19 [SJ25C1]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: FC; Size: 100 tests
Supplier:
Biolegend
Description:
PE/Cy7 anti-human CD185 (CXCR5) [J252D4]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: FC; Size: 100 tests
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