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electrophoresis+reagents+HyClone+products+(Cytiva)
Supplier:
Chemglass
Description:
The Glas-Col® micro mantle provides precise heat control for small spherical flasks.
Supplier:
QUALITY BIOLOGICAL, INC.
Description:
DEPC Treated Water is Ultra Pure and prepared by reverse osmosis, passed through fine carbon, de-ionized through two resin beds and serially filtered 1 µm positively charged membranes. The water is subsequently treated with 0.1% (v/v) DEPC (Diethylpyrocarbonate) and incubated and heated overnight at 37°C. Finally, DEPC Treated Water is filtered through a 0.1 µm filter.
Catalog Number:
(89367-504)
Supplier:
Genetex
Description:
p38 is a 38 kDa Stress Activated Protein Kinase / Map Kinase (SAPK / MAPK) that is fully activated by dual phosphorylation on threonine 180 and tyrosine 182, within the activation loop. p38 MAPK plays a critical role in the initiation of G2 delay after ultraviolet radiation; gene knock-out studies have also revealed a critical role for p38 in cardiac remodeling. Downstream targets of p38 include the transcription factors ELK1 and ATF2 and the kinases MAPKAPK2 and MAPKAPK5. p38 MAPK plays a role in the production of IL-6 and is thought to stabilize erythropoietin production during hypoxic stress. It is activated by environmental stress, many pro-inflammatory cytokines and lipopolysaccharide. Dual phosphorylation by MAP2K3 and MAP2K6 is required for activation of p38 MAPK. It interacts with MAX, Cdc25B, Cdc25C and binds to the kinase interaction domain in the protein tyrosine phosphatase PTPRR; this interaction retains p38 MAPK in the cytoplasm.
Supplier:
Thermo Scientific Chemicals
Description:
Xanthine oxidase inhibitor; decreases uric acid production
Catalog Number:
(CA100216-948)
Supplier:
Teknova
Description:
For use with recombinant <i>E. coli </i>strains harboring plasmids such as pBluescript, pGEM, pUC series plasmids. Used when the media cannot contain any animal products.
Catalog Number:
(CA009-0134)
Supplier:
Rockland Immunochemical
Description:
Absorption Wavelength: 550 nm. Preservative: None. This product was prepared from normal serum by a multi-step process which includes delipidation and selective precipitation followed by extensive dialysis against the buffer stated, above.
Catalog Number:
(76207-862)
Supplier:
HexArmor
Description:
Microfiber sleeve, designed for use with HexArmor safety glasses.
Catalog Number:
(CAAAAL13999-MD)
Supplier:
Thermo Scientific Chemicals
Description:
For synthesis of optically active products
Supplier:
ROEMER INDUSTRIES, INC.
Description:
PharmaRoam25 is a medical-grade, countertop refrigerator or freezer that has optional accessories such as battery power and data management. Designed to transport vaccines and pharmaceuticals, units function as refrigerators or freezers down to 1 °C (optional -20 °C with refrigerant change) and run on a battery while on the move. These units can be secured with a padlock, have handles on the sides and can be stacked with stacking corners. Excellent for disaster preparedness to store temperature sensitive products when the electrical power supply is not reliable or dependable.
Catalog Number:
(61222-617)
Supplier:
Bel-Art Products
Description:
This total immersion thermometer indicates critical temperature ranges for blood bank refrigerators and vaccine storage
Supplier:
Bel-Art Products
Description:
Polypropylene plastic valve with neoprene valve disk stops the reverse flow of liquid when pressure is interrupted.
Catalog Number:
(10369-556)
Supplier:
Bioss
Description:
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain, such as isoform 2 and isoform 3, may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. Isoform 2 plays an important role as negative regulator of VEGFA- and VEGFC-mediated lymphangiogenesis by limiting the amount of free VEGFA and/or VEGFC and preventing their binding to FLT4. Modulates FLT1 and FLT4 signaling by forming heterodimers. Binding of vascular growth factors to isoform 1 leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate and the activation of protein kinase C. Mediates activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Mediates phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, reorganization of the actin cytoskeleton and activation of PTK2/FAK1. Required for VEGFA-mediated induction of NOS2 and NOS3, leading to the production of the signaling molecule nitric oxide (NO) by endothelial cells. Phosphorylates PLCG1. Promotes phosphorylation of FYN, NCK1, NOS3, PIK3R1, PTK2/FAK1 and SRC.
Supplier:
Shenandoah Biotechnology
Description:
Interleukin 33 (IL-33) is a member of the IL-1 cytokine family and is constitutively expressed in smooth muscle and airway epithelial cells. IL-33 signals through the interleukin 1 receptor-like 1 (IL-1R1) and interleukin-1 receptor accessory protein (IL1RAP) receptors to ativate NF-κB and MAPK signaling pathways. IL-33 functions to induce type 2 cytokine production in polarized Type 2 helper T (Th2) cells.
Catalog Number:
(RK31451)
Supplier:
Restek
Description:
EPA method 8330 is used to measure explosives residues in water and soil samples, using HPLC with UV detection. Target analytes are nitroaromatic and nitramine explosives and their degradation products. Obtaining pure, neat compounds for Method 8330 reference standards can be very difficult. To ensure the highest quality standards, Restek's Quality Control (QC) lab confirms the identity and purity of mixture components and solvents using one or more of the following techniques: GC-FID, HPLC, GC-ECD, GC-MS, LC-MS, refractive index, and melting point.
Catalog Number:
(10401-946)
Supplier:
Bioss
Description:
Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria.
Supplier:
Bel-Art Products
Description:
Epoxy-coated steel wire baskets hold up under the most severe laboratory conditions and are handy for transporting and batch dipping glassware.
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