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electrophoresis+reagents+HyClone+products+(Cytiva)
Supplier:
PIP
Description:
The MaxiFlex® Ultimate™ has become the benchmark for precision handling in dry environments.
Catalog Number:
(56620-394)
Supplier:
New Pig
Description:
Overpack drum container is UN Rated for shipping waste after spill cleanup
Catalog Number:
(76028-250)
Supplier:
Berkshire
Description:
The Cleanroom string mop wringer is made of durable plastic, and is suitable for the one-step wet cleaning process.
Catalog Number:
(70690-118)
Supplier:
Bel-Art Products
Description:
Side opening tube clamp permits installation onto tubing without disconnecting from apparatus or interrupting operation.
Supplier:
Spectrum Chemicals
Description:
PHOSPHORIC ACID, NF is a also known under the name orthophosphoric acid. A mineral acid that is most often presented as a nonvolatile and clear liquid that has a viscous texture. It has a wide field of uses, such as a buffering agent in aqueous solutions, used as a food additive in many soft drinks and in orthodontics as an etching solution. Spectrum Chemical NF products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
Storage temperature - Keep tightly closed
Catalog Number:
(10428-974)
Supplier:
Bioss
Description:
Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
Catalog Number:
(77435-278)
Supplier:
PRECISIONARY INSTRUMENTS LLC
Description:
Live one-on-one video session with cryostat technician on using and installing the cryostat from beginning to end. Includes session for Q&A to help you succeed in your experiments and making the best tissue slices.
Supplier:
Puritan Medical Products
Description:
These swabs have thermal edge seals and thermal bonding to the nadle help ensure the sponge-like foam will clean up unwanted particles without releasing any into your critical environment.
Catalog Number:
(89360-966)
Supplier:
Genetex
Description:
MDM2 is a nuclear phosphoprotein with an apparent molecular mass of 90 Kd that forms a complex with the p53 tumor suppressor protein. Human MDM2 was identified as a homologous product of the 'murine double minute 2' gene (mdm2). The MDM2 gene enhances the tumorigenic potential of cells when it is overexpressed and encodes a putative transcription factor. Forming a tight complex with the p53 gene, the MDM2 oncogene can inhibit p53-mediated transactivation. MDM2 binds to p53 and amplification of MDM2 in sarcomas leads to escape from p53-regulated growth control. This mechanism of tumorigenesis parallels that for virus-induced tumors in which viral oncogene products bind to and functionally inactivate p53. Overexpression of the MDM2 oncogene was found in leukemias. Inactivation of tumor suppressor genes leads to deregulated cell proliferation and is a key factor in human tumorigenesis. MDM2 interacts physically and functionally with the retinoblastoma (RB) protein and can inhibit its growth regulatory capacity. Both RB and p53 can be subjected to negative regulation by the product of a single cellular protooncogene. The interference of binding to p53 prevents the interaction of MDM2 and its regulation of the transcriptional activity of p53 in vivo. Direct association of p53 with the cellular protein MDM2 results in ubiquitination and subsequent degradation of p53. MDM2-p53 complexes were preferentially found in S/G2M phases of the cell cycle. MDM2 maps to 12q14.3-q15, distal to CDK4 and flanked by Genethon microsatellites D12S80 and D12S83. On both the physical and the genetic maps of chromosome 12, the IFG gene maps close to the locus of the MDM2 oncogene on 12q15. The MDM2 gene is alternatively spliced, producing 5 additional splice variant transcripts from the full length MDM2 gene. Four out of five of these alternatively spliced forms (MDM2a-MDMd) are missing substantial portions of the p53-binding domain and retain the acidic domain and the zinc-finger domains. The fifth and smallest transcript (MDM2e) retains the largest spliced region encoding the p53-binding domain; however, it lacks the nuclear localization signal, the acidic domain and zinc-finger domains. The alternatively spliced transcripts tend to be expressed in tumorigenic tissue, whereas the full length MDM2 transcript is expressed in normal tissue.
Catalog Number:
(10837-120)
Supplier:
Bel-Art Products
Description:
Made of soft, clear, flexible vinyl that conforms to the face and nose, these goggles have four vents to reduce fogging.
Catalog Number:
(57952-250)
Supplier:
Bel-Art Products
Description:
This large stainless steel lab spoon is 30.5 cm (12") long for reaching into larger bottles.
Catalog Number:
(89359-966)
Supplier:
Genetex
Description:
The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a andC3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes.
Catalog Number:
(76271-420)
Supplier:
Harvard Apparatus
Description:
Reusable Oocyte Petri electrodes are ideal for electroporation of oocytes, embryos or other cell types in small volumes.
Catalog Number:
(RC314232)
Supplier:
Ricca Chemical
Description:
0.025 (+/-0.00001) Normal (N/40). Meets ASTM D 1252 and EPA Specifications. Container: Glass.
Supplier:
Ricca Chemical
Description:
CAS RN 1310-58-3. Solution, 0.500N in methanol. Packaged in a plastic container. Subject to postal/shipping restrictions. 4L.
Supplier:
Ricca Chemical
Description:
4% (w/v) Aqueous Solution. Ammonia Absorbent. Plastic Container. 1L
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