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electrophoresis+reagents+HyClone+products+(Cytiva)
Catalog Number:
(10423-360)
Supplier:
Bioss
Description:
LEFTY2 is a member of the TGF-beta family of proteins. LEFTY2 is secreted and plays a role in left-right asymmetry determination of organ systems during development and may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene.
Catalog Number:
(10412-044)
Supplier:
Bioss
Description:
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors.
Catalog Number:
(10400-448)
Supplier:
Bioss
Description:
Gross cystic disease is a common premenopausal disorder in which gross cysts are the predominant pathologic lesion. It is characterized by production of a fluid secretion which accumulates in the breast cysts. Gross cystic disease fluid is a pathologic secretion from breast composed of several glycoproteins, including a unique 15 kDa monomer protein, GCDFP 15. The cells within the body that produce GCDFP 15 appear to be restricted primarily to those with apocrine function. Studies have found GCDFP 15 to be a highly specific and sensitive marker for breast cancer.
Catalog Number:
(10230-524)
Supplier:
Bioss
Description:
Secretin belongs to the glucagon family. This protein is an endocrine hormone and its major site of production is the endocrine S cells located in the proximal small intestinal mucosa. The release of active secretin is stimulated by either fatty acids or an acidic pH in the duodenum. This hormone stimulates the secretion of bicarbonate-rich pancreatic fluids and has also been shown to regulate the growth and development of the stomach, small intestine, and pancreas. Secretin deficiency has been implicated in autistic syndrome, suggesting that the hormone could have a neuroendocrine function in addition to its role in digestion.
Catalog Number:
(10764-818)
Supplier:
Prosci
Description:
The 37.51 monoclonal antibody specifically reacts with mouse CD28 molecule, a 45 kDa homodimer. It is expressed on most thymocytes, at low density on most of the CD4+ and CD8+ peripheral T lymphocytes, and on the natural killer cells. It is additionally found on activated splenocytes, mast cells, and thymocytes. CD 28 is a costimulator of T lymphocytes and a ligand for CD80 (B7-1), and CD86 (B7-2). The CD28 signaling stimulates the expression of IL-2 and IL-2 receptor and the cytotoxicity of CD3-activated T lymphocytes.The 37.51 antibody stimulates the proliferation of T lymphocytes and natural killer cells and their respective cytokine production.
Catalog Number:
(10404-398)
Supplier:
Bioss
Description:
Nox4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. Nox4 is also expressed in fetal tissues, placenta, glioblastoma and vascular cells. Like gp91-phox, the enzymatic activity of Nox4 produces superoxide anions. In vascular cells, the addition of angiotensin II increases Nox4 expression, which suggests a role for Nox-4 in vascular oxidative stress response.
Supplier:
Thermo Scientific Chemicals
Description:
For synthesis of optically active products
Catalog Number:
(RK30081)
Supplier:
Restek
Description:
Standard is packaged in purge-and-trap-grade methanol at a concentration of 2500 µg/mL in a 1 mL ampoule.
Supplier:
Medegen Medical Products, LLC
Description:
Heavy-duty hamper stands are made from <sup>7</sup>/<sub>8</sub>" chrome-plated steel tubing with a lower support platform. They are ideal for heavyweight applications.
Supplier:
PIP
Description:
Used for formal occasions by police, firemen, waiters, marching bands, military and pallbearers.
Catalog Number:
(10062-314)
Supplier:
Prosci
Description:
FOXP3 Antibody: FOXP3 is a member of the forkhead/winged-helix family of transcriptional regulators. FOXP3 acts as a repressor of transcription and regulates T cell activation, with its overexpression in CD4 T cells leading to an attenuation of activation-induced cytokine production and proliferation. In regulatory T (Treg) cells, FOXP3 is essential for Treg suppressor function and its expression leads to the repression of IL-17 expression. Genetic mutations involving FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome.
Supplier:
Bachem Americas
Description:
The pentapeptide Ac-LPFFD-NH₂ (iAβ5p) is an analog of product H-4876 with small chemical modifications which enhance its stability against proteolytic degradation. iAβ5p acts as a β-sheet breaker peptide and crosses the blood-brain barrier at a higher rate than most proteins and peptides known to be selectively taken up by the brain so that it is assumed that the peptide is being specifically transported to the brain. A significant increase in neuronal survival and decrease in brain inflammation associated with the reduction of amyloid plaques in two different transgenic Alzheimer`s disease (AD) models is additionally reported for iAβ5p.
Catalog Number:
(89318-098)
Supplier:
Genetex
Description:
Rabbit Polyclonal antibody to cKrox
Catalog Number:
(CA76628-848)
Supplier:
LIFE TECHNOLOGIES CORP CA
Description:
BiTek Proteose Peptone is an enzymatic digest of protein, developed as an alternative to Bacto Proteose Peptones for scale-up to production applications.
Supplier:
Thermo Scientific Chemicals
Description:
In chlorination of organic substances, as an intermediate, and in the production of pure metal
Catalog Number:
(76191-774)
Supplier:
Sklar
Description:
All Sklar products are industry standard.
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