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BIOTIUM, INC
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BIOTIUM, INC
Supplier:
Biotium
Description:
Cytokeratin 7 Monoclonal antibody, Clone: OV-TL12/30, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF647, Immunogen: OTN 11, ovarian carcinoma cell line, Synonyms: CK-7, K2C7, Keratin 55K Type II, Application: IF, IHC, Size: 100uL
Supplier:
Biotium
Description:
HLA-DRB, Monoclonal antibody, Clone: LN-3 + HLA-DRB/1067, Host: Mouse, Species reactivity: Human, Monkey, Isotype: IgG's, Conjugate: CF405S, Immunogen: Activated human peripheral blood mononuclear cells (LN-3 & HLA-DRB/1067), Application: IF, IHC Western, Size: 500uL
Supplier:
Biotium
Description:
HLA-DRB, Monoclonal antibody, Clone: LN-3 + HLA-DRB/1067, Host: Mouse, Species reactivity: Human, Monkey, Isotype: IgG's, Conjugate: CF488A, Immunogen: Activated human peripheral blood mononuclear cells (LN-3 & HLA-DRB/1067), Application: IF, IHC Western, Size: 500uL
Supplier:
Biotium
Description:
Cytokeratin 18 Monoclonal antibody, Clone: DC10, Host: Mouse, Species reactivity: Human, Isotype: IgG1, Conjugate: CF594, Immunogen: PMC-42 human breast carcinoma cells, Synonyms: K18, Application: IF, IHC, WB, FC, Size: 100uL
Supplier:
Biotium
Description:
Cyclin B1 Monoclonal antibody, Clone: CCNB1/1098, Host: Mouse, Species reactivity: Mouse, Human, Isotype: IgG1, kappa, Conjugate: CF594, Immunogen: Recom human full-length CCNB1 protein, Synonyms: CCNB, CCNB1, Application: IF, IHC, FC, Size: 100uL
Supplier:
Biotium
Description:
Cytokeratin 18 Monoclonal antibody, Clone: DC10, Host: Mouse, Species reactivity: Human, Isotype: IgG1, Conjugate: CF568, Immunogen: PMC-42 human breast carcinoma cells, Synonyms: K18, Application: IF, IHC, WB, FC, Size: 500 uL
Supplier:
Biotium
Description:
This MAb recognizes a protein of 165 kDa, identified as carbamoyl phosphate synthetase 1 (CPS1). This mitochondrial enzyme catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells.Deficiency of CPS1 is an autosomal recessive disorder that causes hyperammonemia. CPS1 is a hepatocyte specific protein that localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC s occur primarily in the stomach, but they are also found in many other organs. CPS1 may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of CPS1 correlates with smaller tumor size and longer patient survival. Occasionally, CPS1 is also found in gastric carcinomas as well as in a few other non-hepatic tumors.
Supplier:
Biotium
Description:
This antibody recognizes a protein of 185 kDa, which is identified as c-erbB-2/HER-2/neu. Its epitope is localized in the extracellular domain. C-erbB-2/HER-2 is a member of the EGFR family. This MAb is specific and shows minimal cross-reaction with other members of the EGFR-family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. c-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.
Supplier:
Biotium
Description:
Hepatocyte Specific, Monoclonal antibody, Clone: OCH1E5, Host: Mouse, Species reactivity: Human, Dog, Isotype: IgG1, kappa, Conjugate: CF488A, Immunogen: Recombinant human CPS1 protein, Synonyms: Carbamoylphosphate synthetase 1, Size: 500uL
Supplier:
Biotium
Description:
HLA-DRB, Monoclonal antibody, Clone: LN-3, Host: Mouse, Species reactivity: Human, Monkey, Isotype: IgG's, Conjugate: CF594, Immunogen: Activated human peripheral blood mononuclear cells (LN-3 & HLA-DRB/1067), Application: Immunofluorescence, Size: 100uL
Supplier:
Biotium
Description:
This antibody reacts with a protein of 57 kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody This antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-This antibody reacts with HPV37.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.
Supplier:
Biotium
Description:
HER-2 / CD340, Monoclonal antibody, Clone: HRB2/258, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF488A, Immunogen: Recombinant intracellular domain of human HER-2 protein, Synonyms: p185, CD340, Verb b2, Size: 500uL
Supplier:
Biotium
Description:
Human Nuclear Antigen, Monoclonal antibody, Clone: 235-1, Host: Mouse, Species reactivity: Human, Non-human primates, Isotype: IgG1, kappa, Conjugate: purified, Immunogen: Nuclei of human myeloid leukemia biopsy cells, Synonyms: HNA, Application: IF, Size: 100uL
Supplier:
Biotium
Description:
IDH1, Monoclonal antibody, Clone: IDH1/1152, Host: Mouse, Species reactivity: Human, Isotype: IgG1 and IgG2a, kappa, Conjugate: CF647, Immunogen: Recombinant fragment (119 Amino acid residues around aa 280-420) of human IDH1 protein, Application: IF, IHC Western, Size: 100uL
Supplier:
Biotium
Description:
This antibody recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
Supplier:
Biotium
Description:
Involucrin, Monoclonal antibody, Clone: SY5, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF647, Immunogen: Purified involucrin from human keratinocytes, Synonyms: IVL, Application: Immunofluorescence, Flow cytometry, Size: 100uL
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