BIOTIUM, INC
Supplier:
Biotium
Description:
Helicobacter pylorI, Monoclonal antibody, Clone: HP/212, Host: Mouse, Species reactivity: Helicobacter pylori, Isotype: IgG1, kappa, Conjugate: biotin, Immunogen: Total sonicate of Helicobacter pylori, Synonyms: H. Pylori, Application: IF, Size: 100uL
Supplier:
Biotium
Description:
Cytokeratin, HMW Monoclonal antibody, Clone: KRTH/1076, Host: Mouse, Species reactivity: Human, Rat, Isotype: IgG1, kappa, Conjugate: CF640R, Immunogen: Recom human KRT76 protein, Synonyms: KRT2B, KRT2P, HUMCYT2A, Application: IF, WB, FC, Size: 500 uL
Supplier:
Biotium
Description:
CD32 Monoclonal antibody, Clone: 7.3, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF568, Immunogen: K562 and FcgRII L cellsUnigene 352642, Application: Immunofluorescence, Flow cytometry, Size: 500 uL
Supplier:
Biotium
Description:
This MAb recognizes granulocyte-colony stimulating factor (G-CSF) in the cytoplasm of mature granulocytes. It shows no reactivity with any other cell types. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. It reacts with early precursor and mature forms of myeloid cells. It is useful for the detection of myeloid leukemias and granulocytic sarcomas. It can be used as a marker of granulocytes in normal tissues or inflammatory processes.G-CSF is a pleiotropic cytokine that influences differentiation, proliferation and activation of the neutrophilic granulocyte lineage. The human G-CSF cDNA encodes a 207 amino acid precursor containing a 29 amino acid signal peptide that is proteolytically cleaved to form a 178 amino acid residue mature protein. Two G-CSF's, which are identical except for a three amino acid deletion in the amino-terminus of one form of the protein have been isolated from human cells. Murine and human G-CSF's share 73% sequence identity at the amino acid level.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.
Supplier:
Biotium
Description:
CD31 / PECAM-1 Monoclonal antibody, Clone: C31.3 + C31.7 + C31.10, Host: Mouse, Species reactivity: Rabbit, Cynomolgus monkey, Rat, Human, Isotype: IgG1, K, Conjugate: CF488A, Immunogen: Human Recom CD31, Synonyms: EndoCAM, Application: IF, Size: 100uL
Supplier:
Biotium
Description:
This antibody recognizes a single chain glycoprotein of 105/120 kDa, identified as CD30/Ki-1. CD30 is synthesized as a 90 kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120 kDa glycoprotein. In Hodgkins disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This MAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).
CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.
Supplier:
Biotium
Description:
CD34 Monoclonal antibody, Clone: QBEnd/10, Host: Mouse, Species reactivity: Human, Rhesus monkey, Cynomolgus monkey, Isotype: IgG1, K, Conjugate: purified, Immunogen: Detergent solubilized vesicular suspension prepared, Synonyms: HPCA1, Application: IF, Size: 100uL
Supplier:
Biotium
Description:
GnRH-Receptor (LHRH Receptor), Monoclonal antibody, Clone: F1G4, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF405S, Immunogen: A synthetic peptide aa 1-29 from the N-terminal of human GnRH receptor, Application: IF, Flow, Size: 100uL
Supplier:
Biotium
Description:
CD74 Monoclonal antibody, Clone: LN-2 + CLIP/813, Host: Mouse, Species reactivity: Human, Isotype: IgG's, Conjugate: CF488A, Immunogen: SU-DHL-4 lymphoma cells ; Recombinant full-length human CD74 protein, Application: IF, IHC, FC, Size: 500 uL
Supplier:
Biotium
Description:
Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
Supplier:
Biotium
Description:
This antibody recognizes CK1, CK5, CK10 and CK14. In normal epithelia, it stains stratified epithelia, myoepithelial cells and basal cells in the prostate gland and bronchi. This MAb shows no reactivity with hepatocytes, pancreatic acinar cells, proximal renal tubules, or endometrial glands; there is no reactivity with cells derived from simple epithelia. Mesenchymal tumors, lymphomas, melanomas, neural tumors, and neuroendocrine tumors are negative with this antibody. It stains myoepithelial cells and has been shown to be useful in distinguishing prostate adenocarcinoma from benign prostate. This antibody has also been useful in separating benign from malignant intraductal breast proliferations.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.
Supplier:
Biotium
Description:
CD74 Monoclonal antibody, Clone: LN-2 + CLIP/813, Host: Mouse, Species reactivity: Human, Isotype: IgG's, Conjugate: biotin, Immunogen: SU-DHL-4 lymphoma cells ; Recombinant full-length human CD74 protein, Application: IF, IHC, FC, Size: 100uL
Supplier:
Biotium
Description:
This antibody recognizes a protein of 80 kDa-90 kDa, identified as CD36. It is expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P. falciparum malaria-infected erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4% of Japanese and East Asia population lack CD36.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.
Catalog Number:
(75908-574)
Supplier:
Biotium
Description:
This antibody recognizes a protein of 18-35 kDa, identified as CD90 (also known as Thy1). CD90 is a member of the immunoglobulin superfamily. It may contribute to inhibition of proliferation/differentiation of hematopoietic stem cells and neuron memory formation in the CNS. It consists of a single Ig domain (112 amino acids; 25-35 kDa) inserted into the cell membrane via a GPI anchor. Expressed by hematopoietic stem cells and neurons in all species studied. Its highly expressed in connective tissue and various fibroblast and stromal cell lines, expressed on all thymocytes and peripheral T cells in mice, but in humans expressed only on small % fetal thymocytes, 10-40% of CD34 cells in bone marrow, and <1% of CD3 CD4 lymphocytes in peripheral circulation. It is also expressed by human lymph node HEV endothelium but not other endothelia. Lastly, it is expressed by a limited number of lymphoblastoid and leukemic cell lines.
Supplier:
Biotium
Description:
CGA Monoclonal antibody, Clone: CHGA/765, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF405S, Immunogen: Recom human chromogranin A protein, Synonyms: Beta-Granin, CGA, ER-37, Application: IF, IHC, FC, Size: 100uL
Catalog Number:
(75910-778)
Supplier:
Biotium
Description:
This antibody recognizes a protein of 74 kDa, identified as CD84. It is expressed on mature B cells and on B-cell lines, including pre-B-cell lines, but not on plasma cell lines. Immunohistochemical studies demonstrated that CD84 strongly expressed on tissues macrophages. CD84 is also highly expressed on platelets and, at low levels on peripheral blood T cells. It is a highly N-glycosylated protein and belongs to immunoglobulin superfamily. It may play a role in leukocyte activation.
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