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Mass+Spectrometry
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Mass+Spectrometry
Catalog Number:
(10852-544)
Supplier:
Restek
Description:
Compact ferrules fit fused silica columns with internal diameters ≤0.28 mm.
Supplier:
PeproTech, Inc.
Description:
Mature Myostatin is obtained by proteolytic processing of a biologically-inactive precursor protein, which contains an N-terminal propeptide of 243 amino acid residues. Myostatin-Propeptide exhibits high binding affinity for myostatin, and has been shown to be a potent inhibitor of myostatin. Over-expression of myostatin-propeptide in mice resulted in large increases (up to 200%) in skeletal muscle mass, similar to those observed in myostatin knockout mice. Recombinant Human Myostatin-Propeptide is a 27.8 kDa protein consisting of 244 amino acid residues.
Supplier:
Enzo Life Sciences
Description:
The 19S regulatory complex consists of a ‘base’ sub-complex, composed of a hetero-hexameric ring of AAA-ATPases that not only function as the gate-opener to the 20S proteasome but also, in conjunction with two other high-molecular-mass non-ATPase subunits (Rpn2/S1 and Rpn1/S2), as a platform for protein unfolding. The ‘lid’ sub-complex of the 19S complex, composed of non-ATPase subunits is involved in the binding and deubiquitinylation of proteasome targeted ubiquitin conjugated proteins and assists in the transport of substrates through the ‘base’ and into the 20S catalytic core.
Supplier:
G-Biosciences
Description:
G-Biosciences' avidin is a glycoprotein with approximately 10% of its total mass comes from carbohydrates
Catalog Number:
(CAPI90076)
Supplier:
LIFE TECHNOLOGIES CORP CA
Description:
Anti-TMT™ Antibody resin enables selective enrichment of peptides in complex samples that have been labeled with Tandem Mass Tag™ Reagents.
Catalog Number:
(77439-166)
Supplier:
Bioss
Description:
Osteoprotegerin (OPG, or osteoclastogenesis inhibitory factor) is a secretory glycoprotein belonging to TNF receptor superfamily. Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis. Bone homeostasis seems to depend on the local RANKL/OPG ratio. May also play a role in preventing arterial calcification. May act as decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis. OPG acts as a soluble factor in the regulation of bone mass and may be beneficial in the treatment of osteoporosis with increased osteoclast activity. OPG consists of 401 amino acids with a molecular weight of 44 kDa as a monomer and 90 kDa as a disulphide-linked dimer.
Catalog Number:
(10750-810)
Supplier:
Prosci
Description:
CDX2 Antibody: CDX2 is a member of the caudal homeobox family of transcription factors that also includes the proteins CDX1 and CDX4. CDX2 is strongly expressed in the trophectoderm in the blastocyst with expression maintained within the proliferating extra-embryonic ectoderm during development. It is required for the repression of the transcription of the POU5F1/Oct4 and NANOG genes in the outer cells of the blastocyst and is thus essential for the segregation of the inner cell mass and trophectoderm at the blastocyst stage. Aberrant expression of CDX2 is associated with numerous types of carcinomas, including intestinal metaplasia, gastric carcinoma, and acute myeloid leukemia due to deregulated HOX gene expression.
Supplier:
Ricca Chemical
Description:
Acetone 67-64-1 ACS (99.87%)
Picric Acid 88-89-1 ACS (0.09%) Water 7732-18-5 ACS (0.04%) Test Specification Result : Appearance Yellow liquid Volumetric glassware complies with Class A tolerance requirements of ASTM E 288 and NIST Circular 434; it is calibrated before first use and recalibrated regularly in accordance with ASTM E 542 and NIST Procedure NBSIR 74-461. Balances are calibrated regularly with weights certified traceable to the NIST national mass standard. Thermometers and temperature probes are calibrated before first use and recalibrated regularly with a thermometer traceable to NIST standards. All products are prepared according to master documents that assure manufacture according to validatedmethods. Batch records document raw material traceability and production and testing history for each lot manufactured. 
Catalog Number:
(10454-350)
Supplier:
Bioss
Description:
DRAK1 (DAP kinase-related apoptosis-inducing protein kinase 1) is a novel member of the ser/thr protein kinase family, which mediate apoptosis through their catalytic activities. The full-length cDNA encodes a deduced 414-amino acid protein with a molecular mass of 46.56 kD. DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. DRAK1 messenger RNA appears to be ubiquitously expressed in human tissues. Overexpression of DRAK1 induces apoptosis. It has been shown in vitro that DRAK1 is capable of autophosphorylation and of phosphorylating the myosin light chain as an exogenous substrate, and that the noncatalytic C terminus is crucial for full kinase activity.
Catalog Number:
(10092-366)
Supplier:
Proteintech
Description:
PITRM1 (Presequence protease, mitochondrial) is a ATP-independent protease that degrades mitochondrial transit peptides after their cleavage.It is specific for peptides in the range of 10 to 65 residues.and able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease.It shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.This protein has a calculated molecular mass of 117kD and it is expressed widely.This antibody is specific to PITRM1.
Catalog Number:
(10083-124)
Supplier:
Proteintech
Description:
ARF-like proteins (ARLs) belong to a group of incompletely characterized members in the ARF family of RAS-related GTPases. A 19-kDa protein (BART, Binder of Arl Two) was identified to bind specifically to ARL2.GDP with high affinity but not with ARL2.GDP. In human, the 489-base pair BART open reading frame encodes a novel 163-amino acid protein with a predicted molecular mass of 18,822 Da. Data from Northern and Western analyses indicated BART is expressed in many tissues.
Catalog Number:
(10346-850)
Supplier:
Bioss
Description:
Defects in CYLD are the cause of familial cylindromatosis (CYLD) also known as turban tumor syndrome or dermal eccrine cylindromatosis. CYLD is an autosomal dominant and highly tumor type-specific disorder. The tumors (known as cylindromas because of their characteristic microscopic architecture) are believed to arise from or recapitulate the appearance of the eccrine or apocrine cells of the skin that secrete sweat and scent respectively. Cylindromas arise predominantly in hairy parts of the body with approximately 90% on the head and neck. The development of a confluent mass which may ulcerate or become infected has led to the designation "turban tumor syndrome". The skin tumors show differentiation in the direction of hair structures, hence the synonym trichoepithelioma. CYLD has deubiquitinating activity.
Catalog Number:
(10106-936)
Supplier:
Prosci
Description:
FBN1 is a member of the fibrillin family. FBN1 is a large, extracellular matrix glycoprotein that serve as a structural component of 10-12 nm calcium-binding microfibrils. These microfibrils provide force bearing structural support in elastic and nonelastic connective tissue throughout the body. Mutations in this gene are associated with Marfan syndrome, isolated ectopia lentis, autosomal dominant Weill-Marchesani syndrome, MASS syndrome, and Shprintzen-Goldberg craniosynostosis syndrome.
Catalog Number:
(10085-960)
Supplier:
Proteintech
Description:
FKBP2 is also named as FKBP13 and belongs to the FKBP-type PPIase family. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. FKBP2 has a 21-amino acid signal peptide and appears to be membrane-associated. It is localized to the lumen of the endoplasmic reticulum (ER). FKBP12 and FKBP13 are highly similar proteins, of molecular masses 12 kDa and 13 kDa respectively, with approx.43 % amino acid identity. The strong homology between FKBP12 and FKBP13 suggests that they may share similar biological functions, although, apart from rotamase activity, details relating to the function of either protein are scant.
Catalog Number:
(10087-042)
Supplier:
Proteintech
Description:
FKBP7(FK506-binding protein 7) is also named as FKBP23 and belongs to immunophilin class of proteins family. This protein contains an N-terminal hydrophobic signal sequence, a PPIase motif, 2 EF-hand domains, and 2 putative N-glycosylation sites. The calculated molecular mass is about 25 kD, but becomes 33 kD following cleavage of the signal sequence. It could bind to BiP in ER in a process regulated by the concentration of Ca2+. It has 3 isoforms produced by alternative splicing.
Catalog Number:
(10084-534)
Supplier:
Proteintech
Description:
CDK9(Cyclin-dependent kinase 9) is involved in the regulation of transcription.It has two isforms.CDK9-55 had an apparent molecular mass of 55 kD. The ratio of CDK9-55 to the shorter CDK9 isoform, CDK9-42, differed between HeLa cell nuclear extracts and mouse fibroblasts, but CDK9-42 was the predominant isoform in both.CDK9 is located primarily in the nucleus.
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