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BIOTIUM, INC


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Supplier:  Biotium
Description:   CD31 / PECAM-1 Monoclonal antibody, Clone: C31.10, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: BSA-free, Immunogen: Recom human CD31 protein, Synonyms: EndoCAM, PECA1, Application: IF, IHC, FC, Size: 50 uL
Supplier:  Biotium
Description:   CD68 Monoclonal antibody, Clone: C68/684, Host: Mouse, Species reactivity: Human, Monkey, Isotype: IgG1, Conjugate: CF640R, Immunogen: Recom human CD68 protein, Synonyms: GP110, LAMP4, Application: IF, IHC, FC, Size: 500 uL
Supplier:  Biotium
Description:   This antibody recognizes a protein of 150 kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120-150 kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70-80 kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This MAb This antibody recognizes only the 150 kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.
Supplier:  Biotium
Description:   This MAb recognizes a 60 kDa antigen associated with the mitochondria in human cells. It is a part of a new panel of reagents, which recognizes subcellular organelles or compartments of human cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. It recognizes an antigen associated with the mitochondria in human cells only. It can be used to stain the mitochondria in cell or tissue preparations and can be used as a mitochondrial marker in subcellular fractions. It produces a spaghetti-like pattern in normal and malignant cells and may be used to stain mitochondria of cells in fixed or frozen tissue sections. It can also be used with paraformaldehyde fixed frozen tissue or cell preparations. This MAb is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells, including neurons and embryonic stem cells.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.
Supplier:  Biotium
Description:   CD28 Monoclonal antibody, Clone: C28/77, Host: Mouse, Conjugate: CF405S, Species reactivity: Human, Immunogen: Recombinant human CD28 protein, Isotype: IgG1, kappa, Synonyms:T-cell-specific surface glycoprotein CD28, Application: IF, IHC (formalin), FC, Size: 500 uL
Supplier:  Biotium
Description:   IgM Immunoglobulin, Monoclonal antibody, Clone: IM260, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: biotin, Immunogen: Heavy chain of human IgM, Synonyms: AGM1; IGHM, Application: IF, IHC (formalin), Flow, Size: 500uL
Supplier:  Biotium
Description:   CD5 Monoclonal antibody, Clone: C5/473 + CD5/54/F6, Host: Mouse, Species reactivity: Rabbit, Cow, Rat, Human, Isotype: IgG2a &IgG1, K, Conjugate: CF640R, Immunogen: peptide, Synonyms: CD5 antigen (p56 62), LEU1, Application: IF, Size: 500 uL
Supplier:  Biotium
Description:   This antibody recognizes 78 kDa moesin protein. Moesin, a member of the talin-4.1 superfamily, is a linking protein of the sub-membranous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.
Supplier:  Biotium
Description:   Calcein AM is a widely used green fluorescent cell marker. Calcein AM is membrane-permeant and thus can be introduced into cells via incubation.
Catalog Number: (89139-500)

Supplier:  Biotium
Description:   RuBP-4S ([Ruthenium(bathophenanthroline)(bis(bathophenanthrolinedisulfonate))],disodium salt) is a luminescent ruthenium complex similar to RuBPS (80021). Two of the bathophenanthroline ligands are bis-sulfonated while the third bathophenanthroline ligand is neutral, resulting in an overall double negative charges of the ruthenium complex.
Catalog Number: (89139-512)

Supplier:  Biotium
Description:   Biotium developed SDIP/Eu3 as an alternative to DPA/Tb3 (80104), which is used for vesicle fusion assays. Similar to DPA/TB 3 assay, one population of vesicles can be loaded with the chelator SDIP while another population of vesicles can be loaded with EuCl3. Intense red fluorescence is produced when the two types of vesicles fuse as a result of formation of the SDIP/Eu3 complex.
Supplier:  Biotium
Description:   BrUTP (5-Bromouridine-5′-triphosphate) can be enzymatically incorporated into RNA and detected with anti-BrdU antibodies.

Supplier:  Biotium
Description:   PMA (propidium monoazide) is a high-affinity photoreactive DNA binding dye invented by scientists at Biotium for viability PCR of bacteria and other organisms. The dye is weakly fluorescent by itself but becomes more fluorescent after binding to nucleic acids.
Catalog Number: (89139-294)

Supplier:  Biotium
Description:   Ionomycin is commonly used to modify intracellular calcium concentrations and to calibrate fluorescent calcium indicators. It is also known for its antiproliferative effects.
Catalog Number: (89139-594)

Supplier:  Biotium
Description:   4-Chloro-7-nitrobenzofurazan
Supplier:  Biotium
Description:   6-Carboxy-X-rhodamine is a single isomer, long wavelength rhodamine dye.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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