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BIOTIUM, INC
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BIOTIUM, INC
Catalog Number:
(75882-074)
Supplier:
Biotium
Description:
beta-2-microglobulin Monoclonal antibody, Clone: B2M/1118, Host: Mouse, Species reactivity: Human, Non-human primates, Isotype: IgG2b, kappa, Conjugate: BSA-free, Immunogen: Full length Recom human B2M protein, Synonyms: B2M, Hdcma22p, Size: 50 uL
Supplier:
Biotium
Description:
Mucin 3, Monoclonal antibody, Clone: MUC3/1154, Host: Mouse, Species reactivity: Human, Isotype: IgG2b, kappa, Conjugate: purified, Immunogen: synthetic peptide of 35 amino acids, SIB35, Synonyms: Intestinal mucin-3A; intestinal mucin-like, Application: IF, Size: 100uL
Supplier:
Biotium
Description:
The Pax gene family of nuclear transcription factors comprises nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).
CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.
Supplier:
Biotium
Description:
This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. This MAb is excellent for staining of formalin-fixed, paraffin-embedded breast carcinomas.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.
Catalog Number:
(75965-924)
Supplier:
Biotium
Description:
Neurofilament (NF-L), Monoclonal antibody, Clone: NFL/736, Host: Mouse, Species reactivity: Chicken, Pig, Cow, Rat, Human, Isotype: IgG1 andIgG2a, kappa, BSA-free, Immunogen: Recombinant human NEFL protein, Application: IF, IHC (formalin), Size: 50 uL
Supplier:
Biotium
Description:
P27 / KIP1, Monoclonal antibody, Clone: SX53G8, Host: Mouse, Species reactivity: Mouse, Monkey, Rat, Human, Isotype: IgG's, Conjugate: CF488A, Immunogen: Mouse recombinant p27 protein (DCS-72.F6), Synonyms: CDKN1B, CDKN4, Cyclin Dependent Kinase Inhibitor 1B, Size: 500uL
Supplier:
Biotium
Description:
Biotium offers high quality amine-reactive succinimidyl ester (SE) dyes used to label proteins, oligonucleotides, and nucleic acids.
Supplier:
Biotium
Description:
HCG-beta, Monoclonal antibody, Clone: HCGb/54, Host: Mouse, Species reactivity: Human, Isotype: IgG's, Conjugate: CF405S, Immunogen: Recombinant hCG beta protein (HCGb/54 and HCGb/459), Synonyms: CG-beta; CGB3; CGB5; CGB7; CGB8, Application: Immunofluorescence, Size: 500uL
Supplier:
Biotium
Description:
This antibody recognizes a glycoprotein of 75 kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.
Supplier:
Biotium
Description:
This antibody recognizes a protein of HMW, identified as mucin 3 glycoprotein (MUC3). Its epitope localizes between aa SITTTE. This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC2. MUC3 is distributed in colon and rectum, and is also present to a lesser extent in breast, lung and salivary gland tissues. The Mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs) encoded by 60 base pairs (Mucin 1), 69 base pairs (Mucin 2) and 51 base pairs (Mucin 3). The number of repeats is highly polymorphic and varies among different alleles. Mucin 1 proteins are expressed as type I membrane proteins in addition to secreted forms. Mucin 1 is aberrantly expressed in epithelial tumors including breast carcinomas. Mucin 2 coats the epithelia of the intestines and airways and is associated with colonic tumors. Mucin 3 is a major component of various mucus gels and is broadly expressed in normal and tumor cells.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.
Supplier:
Biotium
Description:
This monoclonal antibody is part of a new panel of reagents, which recognizes subcellular organelles or compartments of human cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. This MAb recognizes the double stranded DNA in human cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in human cells. This MAb produces a homogeneous staining pattern in the nucleus of normal and malignant cells.,Double Stranded deoxyribonucleic acid (ds DNA) is the genetic material of all cells and many viruses and is a polymer of nucleotides. The monomer consists of phosphorylated 2-deoxyribose N-glycosidically linked to one of four bases, adenine, cytosine, guanine or thymine. These are linked together by 3',5'-phosphodiester bridges. In the Watson-Crick double-helix model, two complementary strands are wound in a right-handed helix and held together by hydrogen bonds between complementary base pairs.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Catalog Number:
(89139-258)
Supplier:
Biotium
Description:
5-CFDA is membrane-permeant and thus can be loaded into cells via incubation. Once inside cells, 5-CFDA is hydrolyzed by intracellular esterases to 5-carboxyfluorescein (see 50015).
Catalog Number:
(75959-966)
Supplier:
Biotium
Description:
MART-1 / Melan-A, Monoclonal antibody, Clone: A103, Host: Mouse, Species reactivity: Mouse, Dog, Rat, Human, Isotype: IgG1, kappa, BSA-free, Immunogen: Recombinant hMART-1 protein, Synonyms: Antigen LB39-AA, Application: Immunofluorescence, IHC Western, Size: 50 uL
Supplier:
Biotium
Description:
Llama anti-mouse CF™ dye conjugates are prepared by labeling affinity purified llama anti-mouse IgG (H+L) with a selection of CF™ dyes. CF™ dyes offer combined advantages in brightness, photostability, and specificity compared other fluorescent dyes. CF™594 (Ex/Em 593/614 nm) is a deep-red dye spectrally similar to Alexa Fluor® 594 and Texas Red® dye but yields much brighter protein conjugates due to its high quantum yield and exceptional water solubility. CF™594 also has excellent photostability ideal for demanding applications, such as confocal microscopy and single molecule imaging.
Alexa Fluor® and Texas Red® are registered trademarks of Thermo Fisher Scientific.
Supplier:
Biotium
Description:
Kappa Light Chain, Monoclonal antibody, Clone: Kap-56, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF488A, Immunogen: Purified human Ig kappa chain (HP6053) & Human B-Lymphoma Cells (L1C1), Synonyms: Ig Kappa Chain C Region, Size: 500uL
Supplier:
Biotium
Description:
ACTH Monoclonal antibody, Clone: 57, Host: Mouse, Species: Mouse, Rat, Human, Isotype: IgG1, kappa, Conjugate: CF405S, Immunogen: 39 amino acid active peptide produced by the anterior pituitary, Synonyms: Adrenocorticotropin, Application: IF, Immunohistology, Fc, Size: 500ul
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