BIOTIUM, INC
Supplier:
Biotium
Description:
This antibody recognizes a glycoprotein of 110 kDa, which is identified as CD68. It is important for identifying macrophages in tissue sections. It stains macrophages in a wide variety of human tissues, including Kupffer cells and macrophages in the red pulp of the spleen, in lamina propria of the gut, in lung alveoli, and in bone marrow. It reacts with myeloid precursors and peripheral blood granulocytes. It also reacts with plasmacytoid T cells, which are supposed to be of monocyte/macrophage origin. It shows strong granular cytoplasmic staining of chronic and acute myeloid leukemia and also reacts with rare cases of true histiocytic neoplasia. Lymphomas are negative or show few granules.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®770 is a near-infrared fluorescent dye (Ex/Em 770/797 nm) with exceptional brightness for in vivo imaging or near-IR western blotting.
Supplier:
Biotium
Description:
Transgelin / SM22-alphA, Monoclonal antibody, Clone: TAGLN/247, Host: Mouse, Species reactivity: Mouse, Pig, Cow, Human, Rabbit, Isotype: IgG1, kappa, Conjugate: purified, Immunogen: Recombinant full-length human transgelin protein, Application: IF, Size: 500uL
Supplier:
Biotium
Description:
WT1 (Wilm's Tumor 1), Monoclonal antibody, Clone: 6F-H2, Host: Mouse, Species reactivity: Mouse, Rat, Human, Isotype: IgG1, kappa, Conjugate: CF555, Immunogen: Recombinant protein corresponding to residues 1-181 of human WT1, Synonyms: WT1; AWT1; FWT1, Size: 100uL
Supplier:
Biotium
Description:
Cytokeratin, HMW Monoclonal antibody, Clone: KRTH/1076, Host: Mouse, Species reactivity: Human, Rat, Isotype: IgG1, kappa, Conjugate: CF568, Immunogen: Recom human KRT76 protein, Synonyms: KRT2B, KRT2P, HUMCYT2A, Application: IF, WB, FC, Size: 100uL
Supplier:
Biotium
Description:
SOX10, Monoclonal antibody, Clone: SOX10/991 + SOX10/1074, Host: Mouse, Species reactivity: Human, Isotype: IgG2a, kappa, Conjugate: CF647, Immunogen: Recombinant fragment (aa 115-269) of human SOX10 protein with hexa-histidine tag, Synonyms: DOM; PCWH; SOX10; SRY, Size: 500uL
Catalog Number:
(10066-560)
Supplier:
Biotium
Description:
1,6-Diphenyl-1,3,5-hexatriene (DPH) is almost non-fluorescent in water, but it exhibits a strong increase in fluorescence after intercalation into membranes and can be used as a probe for viscosity, polarity and lipid order.
Supplier:
Biotium
Description:
CD35 / CR1 Monoclonal antibody, Clone: E11, Host: Mouse, Conjugate: CF405S, Species reactivity: Human, Rhesus monkey, Cynomolgus monkey, Baboon, Immunogen: Intact human monocytes, Isotype: IgG1, kappa, Synonyms:C3 binding protein, Application: IF, Size: 100uL
Supplier:
Biotium
Description:
TAG-72 / CA72.4, Monoclonal antibody, Clone: B72.3, Host: Mouse, Species reactivity: Human, Hamster, Dog, Cow, Rat, Isotype: IgG1, kappa, Conjugate: CF405S, Immunogen: Membrane-enriched fraction of breast carcinoma, Synonyms: CA72.4, Size: 500uL
Supplier:
Biotium
Description:
P57 / KIP2, Monoclonal antibody, Clone: KIP2/880, Host: Mouse, Species reactivity: Mouse, Human, Isotype: IgG1, kappa, Conjugate: CF640R, Immunogen: Recombinant human p57Kip2 protein, Synonyms: Beckwith Wiedemann syndrome (WBS); BWCR, Application: IF, IHC, Size: 500uL
Catalog Number:
(75955-664)
Supplier:
Biotium
Description:
Kappa Light Chain, Monoclonal antibody, Clone: KLC264, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, BSA-free, Immunogen: Purified human Ig kappa chain (HP6053) & Human B-Lymphoma Cells (L1C1), Synonyms: Ig Kappa Chain C Region, Size: 50 uL
Supplier:
Biotium
Description:
Anti-IgG Chicken Polyclonal Antibody (CF™ 488A)
Supplier:
Biotium
Description:
Cytokeratin 19 Monoclonal antibody, Clone: BA17, Host: Mouse, Species reactivity: Mouse, Human, Isotype: IgG2a, kappa, Conjugate: biotin, Immunogen: Human mammary epithelial organoids, Synonyms: k19, k1cs, krt19, Application: IF, IHC, FC, Size: 100uL
Supplier:
Biotium
Description:
IL-6 (Rat), Monoclonal antibody, Clone: MP5-20F3, Host: Rat, Species reactivity: Mouse, Isotype: IgG2a, kappa, Conjugate: CF594, Immunogen: Recombinant mouse IL-6 protein, Application: Immunofluorescence, Neutralization, Flow cytometry, Size: 100uL
Catalog Number:
(75975-056)
Supplier:
Biotium
Description:
Thyroglobulin is a 660 kDa dimeric pre-protein with mutiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between primary thyroid and lung neoplasms.
Supplier:
Biotium
Description:
CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.
Supplier:
Biotium
Description:
Transgelin / SM22-alphA, Monoclonal antibody, Clone: TAGLN/247, Host: Mouse, Species reactivity: Pig, Cow, Human, Rabbit, Isotype: IgG1, kappa, Conjugate: CF405S, Immunogen: Recombinant full-length human transgelin (TAGLN) protein, Application: IF, Size: 100uL
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