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BIOTIUM, INC
Supplier:
Biotium
Description:
This MAb recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120 kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi's sarcoma, but with a lower specificity.
Supplier:
Biotium
Description:
CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.
Supplier:
Biotium
Description:
CD106 / VCAM1 Monoclonal antibody, Clone: 1.4C3, Host: Mouse, Species: Human, Isotype: IgG1, kappa, Conjugate: CF647, Immunogen: Recognizes a protein of 110kDa, Synonyms: CD106, INCAM-100, L1CAM, Vascular cell adhesion protein 1, Application: IF, IHC, Fc, Size: 100ul
Supplier:
Biotium
Description:
CD27 Monoclonal antibody, Clone: 203.6, Host: Mouse, Species reactivity: Human, Isotype: IgG3, kappa, Conjugate: CF568, Immunogen: Sezary cells, Synonyms: T14, TNFRSF7, TNFSF7, Tp55, Application: IF, FC, Size: 500 uL
Supplier:
Biotium
Description:
GM-CSF, Monoclonal antibody, Clone: BVD2-21C11, Host: Mouse, Species reactivity: Human, Rhesus monkey, Cynomolgus monkey, Isotype: IgG1, kappa, Conjugate: CF568, Immunogen: Recombinant human GM-CSF protein, Application: Immunofluorescence, Western, Size: 100uL
Supplier:
Biotium
Description:
PLAP (Placental Alkaline Phosphatase), Monoclonal antibody, Clone: ALPP/238, Host: Mouse, Species reactivity: Human, Isotype: IgM, kappa, Conjugate: CF488A, Immunogen: Recombinant full-length human ALPP protein, Application: IF, Immunohistology (formalin), Flow, Size: 500uL
Supplier:
Biotium
Description:
This antibody reacts with Ig domain of CD47 protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50 kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.
Supplier:
Biotium
Description:
Anti-IgG Donkey Polyclonal Antibody (CF™ 633)
Supplier:
Biotium
Description:
CD106 / VCAM1 Monoclonal antibody, Clone: VCAM1/843, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: biotin, Immunogen: Recom human VCAM1 protein, Synonyms: CD106, INCAM-100, L1CAM, Application: IF, IHC, FC, Size: 500 uL
Supplier:
Biotium
Description:
This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. It strongly stains nuclei of epithelial cells in breast carcinomas.
Supplier:
Biotium
Description:
This MAb recognizes a 60 kDa antigen associated with the mitochondria in cells. It is a part of a new panel of reagents, which recognizes subcellular organelles or compartments of cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. It recognizes an antigen associated with the mitochondria in cells from a wide variety of animals, but not insects and bacteria. It can be used to stain the mitochondria in cell or tissue preparations and can be used as a mitochondrial marker in subcellular fractions. It produces a spaghetti-like pattern in normal and malignant cells and may be used to stain mitochondria of cells in fixed or frozen tissue sections. It can also be used with paraformaldehyde fixed frozen tissue or cell preparations.
Supplier:
Biotium
Description:
CD79A Monoclonal antibody, Clone: IGA/764, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF405S, Immunogen: Recombinant human IGA protein, Application: IF, Immunohistology (formalin), FC, Size: 500 uL
Supplier:
Biotium
Description:
Kappa Light Chain, Monoclonal antibody, Clone: HP6053 + L1C1, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF405S, Immunogen: Purified human Ig kappa chain (HP6053) & Human B-Lymphoma Cells (L1C1), Synonyms: HCAK1, Size: 500uL
Supplier:
Biotium
Description:
CD8a (clone SK1) is a validated mouse monoclonal antibody that recognizes CD8a, a transmembrane glycoprotein and co-receptor found in T cells. This antibody derived from the CD8 alpha chain. The antibody is available conjugated to CF® Dyes and Astral™ tandem dyes. They are supplied in PBS, 0.1% BSA, 0.05% azide.
Supplier:
Biotium
Description:
P55;50 EBV-Early Antigen, Monoclonal antibody, Clone: 1108-1, Host: Mouse, Species reactivity: EBV, Isotype: IgG1, kappa, Conjugate: CF640R, Synonyms: EBNA1; EBV nuclear antigen 1; Epstein Barr nuclear antigen 1, Application: Immunofluorescence, Size: 500uL
Supplier:
Biotium
Description:
This antibody recognizes a 180-185 kDa protein, identified as isoform of leukocyte common antigen (CD45RO). This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. It shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. Reportedly, it is useful to identify T-cell lymphomas and leukemias. It rarely stains NK cells or B-cell lymphomas.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.
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 is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
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