BIOTIUM, INC
Supplier:
Biotium
Description:
This antibody recognizes a protein of 75 kDa, identified as γ heavy chain of human immunoglobulins. Its epitope maps in CH2 domain of Fc region of IgG. It reacts with all sub-classes of γ chain of human immunoglobulins. It does not cross-react with α (IgA), μ (IgM), ε (IgE), or δ (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Supplier:
Biotium
Description:
IgG Immunoglobulin, Monoclonal antibody, Clone: IG266, Host: Mouse, Species reactivity: Human, Isotype: IgG's, Conjugate: CF640R, Immunogen: Purified polyclonal human Ig Gamma Chain, Application: Immunofluorescence, Immunohistology (formalin), Flow, Size: 100uL
Supplier:
Biotium
Description:
IgM Immunoglobulin, Monoclonal antibody, Clone: IM260 + ICO-30, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF488A, Immunogen: Heavy chain of human IgM, Synonyms: AGM1; IGHM, Application: IF, IHC (formalin), Flow cytometry, Size: 500uL
Supplier:
Biotium
Description:
Involucrin, Monoclonal antibody, Clone: IVRN/827, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: biotin, Immunogen: Purified involucrin from human keratinocytes, Synonyms: IVL, Application: Immunofluorescence, Flow cytometry, Size: 100uL
Supplier:
Biotium
Description:
This antibody recognizes a protein of 75 kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Supplier:
Biotium
Description:
This antibody recognizes a dimer of two proteins of 70 kDa and ~80 kDa, identified as two subunits of Ku. This MAb This antibody recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460 kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.
Supplier:
Biotium
Description:
Lambda Light Chain, Monoclonal antibody, Clone: Lamb14, Host: Mouse, Species reactivity: Human, Isotype: IgG2a, kappa, Conjugate: purified, Immunogen: Purified IgG myeloma proteins coupled to polyaminostyren, Synonyms: BJP, Application: IF, Size: 100uL
Supplier:
Biotium
Description:
IgA Immunoglobulin, Monoclonal antibody, Clone: IA761, Host: Mouse, Species reactivity: Human, Isotype: IgG1, Conjugate: CF543, Immunogen: Purified human alpha heavy chain, Synonyms: A2m Marker; Ig alpha 1 Chain C Region, Application: IF, IHC (formalin), Size: 100uL
Supplier:
Biotium
Description:
MitoView™ dyes are fluorogenic mitochondrial stains for live cells. The dyes rapidly accumulate in mitochondria and can be imaged without washing. They are available with blue, green, far-red, and near-infrared fluorescence.
Supplier:
Biotium
Description:
AccuBlue™ and AccuClear™ dsDNA quantitation assays provide sensitive, accurate and easy-to-use dsDNA quantitation assays for fluorescent microplate readers in 96-well or 384-well formats.
Supplier:
Biotium
Description:
This MAb recognizes a protein of 145 kDa, identified as CD117/p145kit. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-CD117 has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposi's sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-CD117 is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.
Catalog Number:
(75886-722)
Supplier:
Biotium
Description:
This antibody recognizes a protein of 180 kDa, identified as CD11a (Leucocyte Workshop IV; Code 1524). CD11a complex with the 2 subunit of the integrin family, CD18, to form the cell surface heterodimer, LFA-1 or CD11a /C18 (aLbL). LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses. This MAb potently blocks LFA-1 dependent homotypic cell aggregation.
Supplier:
Biotium
Description:
CD16Monoclonal antibody, Clone: ICO-116, Host: Mouse, Conjugate: CF405S, Species reactivity: Human, Isotype: IgG's, Immunogen: Human CD16 proteinUnigene 372679, Application: Immunofluorescence, Flow cytometry, Size: 100uL
Supplier:
Biotium
Description:
FGF23 Monoclonal antibody, Clone: FGF23/638, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF594, Immunogen: Recombinant human FGF23 protein, Synonyms: ADHR, FGF-23, FGFN, Fibroblast growth factor 23, HPDR2, HYPF, Size: 500 uL
Supplier:
Biotium
Description:
CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.
Supplier:
Biotium
Description:
CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.
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