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BIOTIUM, INC
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BIOTIUM, INC
Supplier:
Biotium
Description:
This antibody recognizes a protein of 32 kDa, identified as CD8a (also known as CD8 chain, T cell co-receptor, Leu2, and T8). CD8 molecule consists of two chains, termed and chain, which are expressed as a disulphide-linked heterodimer or as an homodimer. CD8 is expressed on T cell subset (cytotoxic/suppressor T cells), thymocytes and NK cells. The majority of CD8 T-cells expresses CD8 as heterodimer. Some subpopulation of CD8 T cells as well as NK cells may express homodimer. CD8 functions as a co-receptor in concert with TCR for binding the MHC class I/peptide complex. The HIV-2 envelope glycoprotein binds CD8 chain (but not chain). The cytoplasmic domain of CD8 associates with p56lck tyrosine kinase.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.
Catalog Number:
(75894-886)
Supplier:
Biotium
Description:
CD37 Monoclonal antibody, Clone: IPO-24, Host: Mouse, Species reactivity: Human, Isotype: IgG2b, kappa, Conjugate: BSA-free, Immunogen: Spleen cells of a patient with hairy cell leukemia, Synonyms: GP52 40, Tspan-26, TSPAN26, Application: IF, FC, Size: 50 uL
Catalog Number:
(89139-290)
Supplier:
Biotium
Description:
Ready-to-use solution of Pluronic® F-127, a nonionic detergent useful for solubilizing hydrophobic dye molecules such as AM esters of Fura-2, Fluo-3, Indo-1, or Rhod-2 to facilitate cell loading.
Catalog Number:
(75915-728)
Supplier:
Biotium
Description:
CD66, pan Monoclonal antibody, Clone: C66/195 + C66/261 + C66/1009 + C66/1030, Host: Mouse, Species reactivity: Human, Isotype: IgG's, Conjugate: BSA-free, Immunogen: Recom full-length human CEA, Synonyms: CEACAM5, CD66, Application: IF, Size: 50 uL
Catalog Number:
(97065-672)
Supplier:
Biotium
Description:
Anti-GFP Mouse Monoclonal Antibody (CF™ 594)
Catalog Number:
(89493-166)
Supplier:
Biotium
Description:
Anti-IgG Goat Antibody (CF™ 640R)
Catalog Number:
(89139-374)
Supplier:
Biotium
Description:
DiOC2(3) (3,3′-Diethyloxacarbocyanine, iodide) has been used for measuring membrane potentials in bacteria. The green fluorescent dye forms red fluorescent aggregates with increasing membrane potential. The spectral shifting phenomenon has been exploited to measure membrane potential ratiometrically.
Catalog Number:
(10018-348)
Supplier:
Biotium
Description:
Goat anti-human IgA reacts specifically with IgA heavy chains (α chains) and not with immunoglobulin light chains. To minimize crossreactivity, it has been adsorbed human IgG prior to conjugation. This conjugate is labeled with CF™488A dye. CF™ dyes offer advantages in brightness, photostability, and specificity compared to other fluorescent dyes. Green fluorescent CF™488A (Ex/Em 490/515 nm) is a superior alternative to FITC (or fluorescein) owing to its exceptional brightness and photostability.
Alexa Fluor® is a registered trademark of Thermo Fisher Scientific.
Supplier:
Biotium
Description:
Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.
Supplier:
Biotium
Description:
Complement C4d Monoclonal antibody, Clone: TDM16, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: biotin, Immunogen: Human Complement 4d protein, Application: Immunofluorescence, Flow cytometry, Size: 100uL
Catalog Number:
(75970-008)
Supplier:
Biotium
Description:
PGP9.5 (UCHL-1), Monoclonal antibody, Clone: UCHL1/841, Host: Mouse, Species reactivity: Zebrafish, Pig, Dog, Cow, Sheep, Rat, Human, Rabbit, Isotype: IgG2a, kappa, BSA-free, Immunogen: Native UchL1 (PGP9.5) protein from brain, Application: IF, Size: 50 uL
Catalog Number:
(75969-832)
Supplier:
Biotium
Description:
PGP9.5 (UCHL-1), Monoclonal antibody, Clone: 31A3, Host: Mouse, Species reactivity: Zebrafish, Pig, Dog, Cow, Sheep, Rat, Human, Guinea Pig, Rabbit, Isotype: IgG2a, kappa, BSA-free, Immunogen: Native UchL1 (PGP9.5) protein, Application: Immunofluorescence, Size: 50 uL
Supplier:
Biotium
Description:
CD27 Monoclonal antibody, Clone: 203.6, Host: Mouse, Species reactivity: Human, Isotype: IgG3, kappa, Conjugate: biotin, Immunogen: Sezary cells, Synonyms: T14, TNFRSF7, TNFSF7, Tp55, Application: IF, FC, Size: 500 uL
Supplier:
Biotium
Description:
Cytotoxic T lymphocytes (CTLs) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify melanomas based on their binding to specific monoclonal antibodies. gp100, also designated ME20-M, ME20-S and PMEL 17, is classified as a melanocyte differentiation antigen and is expressed at low levels in normal cell lines and tissues, but is upregulated in melanocytes. gp100 is a highly glycosylated protein. It is also the product of proteolytic cleavage, which results in a secreted protein.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.
Supplier:
Biotium
Description:
This MAb recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC). Its epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.
Supplier:
Biotium
Description:
This MAb recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the
is still displayed and you need assistance, please call us at 1-800-932-5000.
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