BIOTIUM, INC
Supplier:
Biotium
Description:
A high quality biotin-binding protein conjugated to Biotium's signature bright and photostable fluorescent CF® dyes, and a selection of other labels.
Supplier:
Biotium
Description:
P34 / cdk1, Monoclonal antibody, Clone: CDK1/873, Host: Mouse, Species reactivity: Human, Mink, Monkey, Cow, Isotype: IgG1, kappa, Conjugate: purified, Immunogen: Recombinant human CDK1 protein, Application: Immunofluorescence, Flow cytometry, Size: 500uL
Supplier:
Biotium
Description:
This antibody recognizes a dimer of two proteins of 70 kDa and ~80 kDa, identified as two subunits of Ku. This MAb This antibody recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460 kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.
Supplier:
Biotium
Description:
CD43Monoclonal antibody, Clone: SPN/1094, Host: Mouse, Conjugate: CF640R, Species reactivity: Human, Isotype: IgG1, kappa, Immunogen: Recom human SPN protein, Synonyms: GALGP, GPL115, Application: IF, IHC, FC, Size: 500 uL
Catalog Number:
(10001-612)
Supplier:
Biotium
Description:
Polyclonal anti-MYC (EQKLISEEDL) reacts with human c- MYC tagged fusion proteins. The antibody recognizes the epitope tag fused to either the amino- or carboxy- termini of targeted proteins. Polyclonal anti-MYC (EQKLISEEDL) reacts with human c- MYC tagged fusion proteins. The antibody recognizes the epitope tag fused to either the amino- or carboxy- termini of targeted proteins. This conjugate is prepared by labeling polyclonal rabbit anti-MYC IgG (H+L) with CF™640R dye. CF™640R (Ex/Em 642/662 nm) is a novel far-red rhodamine-based dye spectrally similar to Cy®5 and Alexa Fluor® 647. CF™640R is much brighter than Cy®5 and at least as bright as Alexa Fluor® 647 when excited at 633 or 635 nm. However, the most important advantage of CF™640R is its exceptional photostability.
Alexa Fluor® is a registered trademark of Thermo Fisher Scientific. Cy®5 is a registered trademark of GE Healthcare.
Supplier:
Biotium
Description:
WT1 (Wilm's Tumor 1), Monoclonal antibody, Clone: WT1/857 + 6F-H2, Host: Mouse, Species reactivity: Mouse, Rat, Human, Isotype: IgG1, kappa, Conjugate: CF594, Immunogen: Recombinant protein with residues 1-181 human WT1, Synonym: WT1, Size: 500uL
Supplier:
Biotium
Description:
This antibody recognizes 78 kDa moesin protein. Moesin, a member of the talin-4.1 superfamily, is a linking protein of the sub-membranous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.
Supplier:
Biotium
Description:
This antibody recognizes a protein of 75 kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. IgM antibody is prominent in early immune responses to most antigens. Aberrant levels are associated with immune deficiency states, hereditary deficiencies, myeloma, Waldenstrom's macroglobulinemia, chronic infection and hepatocellular disease. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Supplier:
Biotium
Description:
Calgranulin B / MRP-8/-14 Monoclonal antibody, Clone: MAC387, Host: Mouse, Species reactivity: Monkey, Goat, Baboon, Pig, Dog, Cow, Cat, Rat, Human, Isotype: IgG1, K, Conjugate: CF488A, Synonyms: MAC 387 / S100A8/A9 / Macrophage Ag, Size: 500 uL
Supplier:
Biotium
Description:
This MAb recognizes full-length MUC1 in a glycosylation-independent manner and can bind to the fully glycosylated protein. The dominant epitope of this MAb is APDTR in the VNTR region. It reacts with the core peptide of the MUC1 protein, which is a member of a family of mucin glycoproteins that are characterized by high carbohydrate content, O-linked oligosaccharides, high molecular weight (>200 kDa) and an amino acid composition rich in serine, threonine, proline and glycine. The core protein contains a domain of 20 amino-acid tandem repeats that functions as multiple epitopes for the MAb. Incomplete glycosylation of some tumor-associated mucins may lead to variable unmasking of the multiple peptide epitopes leading to the observed differences in staining intensity between normal and malignant tissues. This MAb reacts with both normal and malignant epithelia of various tissues including breast and colon.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.
Supplier:
Biotium
Description:
CD11B Monoclonal antibody, Clone: C11b/660, Host: Mouse, Conjugate: CF640R, Species reactivity: Human, Immunogen: Recombinant human CD11b protein, Isotype: IgG1, kappa, Application: Flow Cytometry, Size: 100uL
Supplier:
Biotium
Description:
Label your antibody with one of our superior CF® Dyes in 30 minutes without a purification step. Labeling tolerates many common buffer components including BSA and ascites.
Supplier:
Biotium
Description:
is labeled with the deep-red fluorescent dye CF594 which is spectrally similar to Alexa Fluor 594 and Texas Red dyes but yields much brighter protein conjugates. CF594 has excellent photostability ideal for demanding applications, such as multi-color imaging.
Supplier:
Biotium
Description:
CD31 / PECAM-1 Monoclonal antibody, Clone: C31.10, Host: Mouse, Conjugate: CF640R, Species reactivity: Human, Immunogen: Recombinant human CD31 protein, Isotype: IgG1, kappa, Synonyms:EndoCAM; PECA1, GPIIA, Application: IF, IHC (formalin), FC, Size: 500 uL
Supplier:
Biotium
Description:
CD106 / VCAM1 Monoclonal antibody, Clone: 1.4C3, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: biotin, Immunogen: Stimulated human umbilical vein endothelial cells, Synonyms: CD106, INCAM-100, L1CAM, Application: IF, Size: 100uL
Supplier:
Biotium
Description:
This antibody recognizes a protein of 40-45 kDa, identified as human milk fat globule membrane protein (HMFG). HMFG is present on normal human breast epithelial cells and cell lines derived from breast carcinomas, as well as to the outer surface of the human milk fat globule. HMFG is considered as a differentiation marker. It is useful as specific breast epithelial marker and can also provide a tool to study the role of the cell surface in normal and neoplastic mammary development.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.
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