BIOTIUM, INC
Catalog Number:
(75964-800)
Supplier:
Biotium
Description:
This antibody recognizes a phosphor-protein of 45 kDa, identified as MyoD1. This MAb does not cross react with myogenin, Myf5, or Myf6. Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilm s tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing s sarcomas and alveolar soft part sarcomas.
Supplier:
Biotium
Description:
CD27 Monoclonal antibody, Clone: 203.6, Host: Mouse, Species reactivity: Human, Isotype: IgG3, kappa, Conjugate: CF488A, Immunogen: Sezary cells, Synonyms: T14, TNFRSF7, TNFSF7, Tp55, Application: Immunofluorescence, Flow cytometry, Size: 100uL
Supplier:
Biotium
Description:
Granulocyte Marker, Monoclonal antibody, Clone: BM-1, Host: Mouse, Species reactivity: Human, Isotype: IgG1, Conjugate: purified, Immunogen: Human peripheral blood mononuclear cells, Synonyms: Myeloid specific protein; p183 DNA-binding cytoplasmic protein, Size: 500uL
Supplier:
Biotium
Description:
MCAM / MUC18 / Mucin 18 / CD146, Monoclonal antibody, Clone: MCAM/1101, Host: Mouse, Species reactivity: Human, Isotype: IgG's, Conjugate: biotin, Immunogen: Recombinant human MCAM protein, Application: Immunofluorescence, Flow cytometry, Size: 100uL
Supplier:
Biotium
Description:
Von Willebrand Factor, Monoclonal antibody, Clone: 3E2D10 + VWF635, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF640R, Immunogen: Recombinant human vWF fragment spanning aa 845-949, Synonyms: Coagulation Factor VIII, Size: 500uL
Supplier:
Biotium
Description:
This product is prepared by labeling IgG with CF350. CF350 is a blue fluorescent dye spectrally similar to AMCA. However, compared to AMCA, CF350 is more water-soluble, more photostable and at least 50% more fluorescent on proteins.
Supplier:
Biotium
Description:
Pmel17 / gp100 / SILV, Monoclonal antibody, Clone: NKI-beteb, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF640R, Immunogen: Extract of pigmented melanoma metastases from lymph nodes, Application: Immunofluorescence, Flow, Size: 500uL
Catalog Number:
(75920-788)
Supplier:
Biotium
Description:
Cytokeratin 8/18 Monoclonal antibody, Clone: C-51, Host: Mouse, Species reactivity: Human, Monkey, Pig, Cow, Sheep, Isotype: IgG1, kappa, Conjugate: BSA-free, Immunogen: Cytoskeleton preparation from HeLa cells, Application: IF, IHC, WB, FC, Size: 50 uL
Supplier:
Biotium
Description:
CD45RA Monoclonal antibody, Clone: 158-4D3, Host: Mouse, Species reactivity: Human, Isotype: IgG2a, kappa, Conjugate: biotin, Immunogen: Stimulated human leukocytes, Synonyms: B220, CD45R, Application: IF, IHC, FC, Size: 100uL
Supplier:
Biotium
Description:
CELA3B Monoclonal antibody, Clone: CELA3B/1218, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF594, Immunogen: Recom human CELA3B protein, Synonyms: ELA3B, Elastase IIIB, Protease E, Application: IF, FC, Size: 500 uL
Supplier:
Biotium
Description:
P21 / WAF1, Monoclonal antibody, Clone: CIP1/823, Host: Mouse, Species reactivity: Human, Isotype: IgG's, Conjugate: CF594, Immunogen: Recombinant full-length human CDKN1A protein (CIP1/823); Human recombinant p21 protein (DCS-60.2), Application: IF, IHC, Size: 100uL
Catalog Number:
(89493-232)
Supplier:
Biotium
Description:
Anti-IgG Donkey Antibody (CF™ 633)
Supplier:
Biotium
Description:
This antibody recognizes a 53 kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53 under denaturing and non-denaturing conditions. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia. Mutations involving p53 are found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®405S is a blue fluorescent dye (Ex/Em 404/431 nm) with superior brightness compared to other blue dyes; it is also compatible with super-resolution imaging by SIM. Note: Conjugates of blue fluorescent dyes are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Catalog Number:
(89139-680)
Supplier:
Biotium
Description:
5-ROX-PEO8 SE (full name: 5-Carboxy-X-rhodamine-PEO8-propionate, succinimidyl ester) has an approximately 32 Angstrom water-soluble PEG spacer that separates the red fluorescent ROX dye and the amine-reactive SE group.
Supplier:
Biotium
Description:
This antibody recognizes a cell surface glycoprotein of 80-95 kDa (CD44) on lymphocytes, monocytes, and granulocytes (Leucocyte Typing Workshop V). Its epitope is resistant to digestion by trypsin and chymotrypsin. The CD44 family of glycoproteins exists in a number of variant isoforms, the most common being the standard 85-95 kDa or hematopoietic variant (CD44s). Higher molecular weight isoforms are described in epithelial cells (CD44v), which are believed to function in intercellular adhesion and stromal binding. CD44 immunostaining is commonly used for the discrimination of urothelial transitional cell carcinoma in-situ from non-neoplastic changes in the urothelium.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.
Catalog Number:
(75973-436)
Supplier:
Biotium
Description:
PTH / Parathyroid Hormone (N-Terminal), Monoclonal antibody, Clone: PTH/1174, Host: Mouse, Species reactivity: Human, Isotype: IgG2b, kappa, BSA-free, Immunogen: synthetic peptide from N-terminal of PTH polypeptide, Synonyms: Parathyrin, Size: 50 uL
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