BIOTIUM, INC
Supplier:
Biotium
Description:
This antibody recognizes a protein of ~76 kDa, which is identified as Nucleolin (NCL). It is the major nucleolar phosphoprotein of growing eukaryotic cells. NCL is located mainly in dense fibrillar regions of the nucleolus. It is found associated with intranucleolar chromatin and pre-ribosomal particles. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly.This MAb can be used to stain the nucleoli in cell or tissue preparations and can be used as a marker of the nucleoli in subcellular fractions. It produces a speckled pattern in the nuclei of cells of normal and malignant cells and may be used to stain the nucleoli of cells in fixed or frozen tissue sections. It can be used with paraformaldehyde fixed frozen tissue or cell preparations and formalin fixed, paraffin-embedded tissue sections.
Supplier:
Biotium
Description:
CD90 Monoclonal antibody, Clone: F15-42-1-5, Host: Mouse, Species reactivity: Human, Monkey, Isotype: IgG1, kappa, Conjugate: CF568, Immunogen: Purified human brain Thy1Unigene 644697, Application: Immunofluorescence, Flow cytometry, Size: 100uL
Supplier:
Biotium
Description:
Anti-IgG Goat Polyclonal Antibody (CF™ 680)
Supplier:
Biotium
Description:
This antibody recognizes a single protein of 33-34 kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia.
CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.
Supplier:
Biotium
Description:
CMV-p65 Monoclonal antibody, Clone: CMV101, Host: Mouse, Species reactivity: CMV, Isotype: IgG1, kappa, Conjugate: CF594, Immunogen: Recombinant CMV-p65 protein, Application: IF, Immunohistology (formalin), Immunohistology (frozen), Size: 500 uL
Supplier:
Biotium
Description:
Myogenin, Monoclonal antibody, Clone: MGN185 + F5D, Host: Mouse, Species reactivity: Pig, Dog, Cat, Rat, Human, Isotype: IgG2a, kappa, Conjugate: CF543, Immunogen: Rat myogenin peptide (aa 73-94), recombinant fragment (aa30-224), Synonym:cb553, Size: 100uL
Supplier:
Biotium
Description:
UACA / Nucling, Monoclonal antibody, Clone: UACA/1222, Host: Mouse, Species reactivity: Mouse, Human, Isotype: IgG's, Conjugate: CF594, Immunogen: Recombinant human UACA protein, Synonyms: Nuclear membrane binding protein, Application: IF, Western, Flow, Size: 100uL
Supplier:
Biotium
Description:
Phosphotyrosine, Monoclonal antibody, Clone: PY20, Host: Mouse, Species reactivity: All species, Isotype: IgG2b, Conjugate: CF488A, Immunogen: Phosphotyrosine conjugated to KLH, Synonyms: P-Tyr, Application: Immunofluorescence, Size: 500uL
Supplier:
Biotium
Description:
Thyroglobulin is a 660 kDa dimeric pre-protein with mutiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between primary thyroid and lung neoplasms.
Catalog Number:
(89493-444)
Supplier:
Biotium
Description:
Anti-IgG Bovine Polyclonal Antibody (CF™ 543)
Supplier:
Biotium
Description:
CD74 Monoclonal antibody, Clone: CLIP/1133, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF405S, Immunogen: Recombinant full-length human CD74 protein, Application: IF, Western, FC, Size: 100uL
Catalog Number:
(75948-890)
Supplier:
Biotium
Description:
GnRH-Receptor (LHRH Receptor), Monoclonal antibody, Clone: GNRHR/768, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, BSA-free, Immunogen: A synthetic peptide aa 1-29 from the N-terminal of human GnRH receptor, Application: IF, Flow cytometry, Size: 50 uL
Supplier:
Biotium
Description:
HIF1A, Monoclonal antibody, Clone: HIF1A-84, Host: Mouse, Species reactivity: Human, Isotype: IgG2b, kappa, Conjugate: purified, Immunogen: Recombinant human HIF1 alpha protein, Application: Immunofluorescence, Flow cytometry, Size: 500uL
Supplier:
Biotium
Description:
This antibody recognizes a protein doublet of 20-22 kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
Supplier:
Biotium
Description:
Cytokeratin 17 Monoclonal antibody, Clone: E3, Host: Mouse, Species reactivity: Goat, Pig, Cow, Rat, Human, Isotype: IgG2b, kappa, Conjugate: CF405S, Immunogen: The cytoskeletal fraction, Synonyms: K17, KRT17, PCHC1, Application: IF, IHC, IHC, Size: 500uL
Supplier:
Biotium
Description:
Thyroglobulin, Monoclonal antibody, Clone: 6E1, Host: Mouse, Species reactivity: Mouse, Rat, Human, Isotype: IgG1, kappa, Conjugate: CF640R, Immunogen: Human thyroid follicular cells, Synonyms: AITD3, Application: Immunohistology (formalin), Flow cytometry, Size: 100uL
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